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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10174/36590
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| Title: | Genome-wide association study identifies genetic variants underlying footrot in Portuguese Merino sheep |
| Authors: | Gaspar, Daniel
Ginja, Catarina
Carolino, Nuno
Leão, Célia
Monteiro, Helena
Tábuas, Lino
Branco, Sandra
Padre, Ludovina
Caetano, Pedro
Romão, Ricardo
Matos, Claudino
Marcos Ramos, António
Bettencourt, Elisa
Usué, Ana |
| Keywords: | Dichelobacter nodosus
footrot
sheep
Merino
Alentejo |
| Issue Date: | 23-Jan-2024 |
| Publisher: | BMC Genomics |
| Citation: | Gaspar, D., Ginja, C., Carolino, N. et al. Genome-wide association study identifies genetic variants underlying footrot in Portuguese Merino sheep. BMC Genomics 25, 100 (2024). https://doi.org/10.1186/s12864-023-09844-x |
| Abstract: | Ovine footrot caused by Dichelobacter nodosus (D. nodosus) is a contagious disease with serious economic and welfare impacts in sheep production systems worldwide. A better understanding of the host genetic architecture regarding footrot resistance/susceptibility is crucial to develop disease control strategies that efficiently reduce infection and its severity. A genome-wide association study was performed using a customized SNP array (47,779 SNPs in total) to identify genetic variants associated to footrot resistance/susceptibility in two Portuguese native breeds, i.e. Merino Branco and Merino Preto, and a population of crossbred animals. A cohort of 1375 sheep sampled across 17 flocks, located in the Alentejo region (southern Portugal), was included in the analyses. |
| URI: | http://hdl.handle.net/10174/36590 |
| Type: | article |
| Appears in Collections: | MED - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica
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MED - Instituto Mediterrâneo para Agricultura, Ambiente e Desenvolvimento /
MED - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica /
