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Title: Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
Authors: Lucena, Sónia
Capela e Silva, Fernando
Lamy, Elsa
Fialho, Luisa
Neves, Sandra
Keywords: Hyperleptinemia
salivar glands
Wistar rats
Issue Date: 2016
Publisher: Experimental Pathology and Health Sciences
Abstract: Saliva production is mainly regulated by the autonomic nervous system (sympathetic and parasympathetic); however studies indicate a possible hormonal influence on the control of salivary secretion. This study aims to assess if the induction of increased levels of circulating leptin influence the immunohistochemical expression of leptin at the level of major salivary glands in Wistar rats. It was found that the expression, in qualitative terms, of leptin has been positive, being more evident in submandibular and sublingual glands, either in the acini or ducts. However, through this technique, no obvious differences between groups could be observed. The results suggest that circulating leptin levels may not affect the expression of this hormone in the major salivary glands.
Type: article
Appears in Collections:MED - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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