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|Title: ||Heat shock response in bacteria with large genomes: lessons from rhizobia|
|Authors: ||Alexandre, Ana|
|Editors: ||de Bruijn, Frans J.|
|Keywords: ||heat stress|
|Issue Date: ||2016|
|Publisher: ||Wiley-Blackwell Publishers|
|Citation: ||Alexandre, A., Oliveira, S. Heat shock response in bacteria with large genomes: lessons from rhizobia, In Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria, 739-746, ISBN: 978-1-119-00488-2. Oxford: Wiley-Blackwell Publishers, 2016.|
|Abstract: ||Rhizobia are important soil bacteria due to their ability to establish nitrogen-fixing symbioses with legume plants. In this dual lifestyle, as free-living bacteria or as plant symbiont, rhizobia are often exposed to different environmental stresses. The present chapter overviews the current knowledge on the heat shock response of rhizobia, highlighting how these large genome bacteria respond to heat from a transcriptional point of view.
Response to heat shock in rhizobia involves genome wide changes in the transcriptome that may affect more than 30% of the genome and involve all replicons. In addition to the expected upregulation of genes already known to be involved in stress response (dnaK, groEL, ibpA, clpB), the reports on the heat shock response in rhizobia also showed particular aspects of stress response in these resourceful bacteria. The transcriptional response to heat in rhizobia includes the overexpression of a large number of genes involved in transcription and carbohydrate transport and metabolism. Additional studies are needed in order to better understand the transcriptional regulation of stress response in bacteria with large genomes.|
|Appears in Collections:||MED - Publicações - Capítulos de Livros|
BIO - Publicações - Capítulos de Livros
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