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Title: Penalized spline smoothing for delay in Pulmonary Tuberculosis diagnosis
Authors: Gomes, Dulce
Filipe, Patrícia A.
Nunes, Carla
de Sousa, Bruno
Editors: Muggeo, Vito M.R.
Capursi, Vincenza
Boscaino, Giovanni
Lovison, Gianfranco
Keywords: Pulmonary Tuberculosis Control
Delay in Diagnosis
Survival Analysis
Issue Date: Jul-2013
Publisher: Università di Palermo
Abstract: In this work, Cox's proportional hazards model with penalized spline functions for time-varying covariate effects are presented in order to model the time between the onset of the first symptoms and the diagnosis of Pulmonary Tuberculosis (PTB) in Portugal. Using this approach revealed a better fitting of the model to the data than Cox's classical model. Results showed that an earlier diagnosis tends to be associated with the following: being male, no alcohol consumption, being diagnosed through active screening, having had a previous PTB treatment, being HIV positive, and being a smoker.
ISBN: 9788896251492
Type: article
Appears in Collections:MAT - Artigos em Livros de Actas/Proceedings

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