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Title: Anticancer drugs in the environment: Environmental levels and technological challenges
Authors: Valente, João Vasco
Coelho, Susana
Pastorinho, M. Ramiro
Sousa, Ana Catarina A.
Editors: Sharma, H
Dominguez, DC
Lee, W-Y
Keywords: Effluents
Environmental Concentrations
Aquatic environment
Issue Date: 2022
Publisher: Elsevier
Abstract: Cytostatic drugs are one of the most used therapeutic agents to treat cancer. However, their high toxicity turns their handling and disposal into a matter of great concern. Upon administration, cytostatics are mainly excreted through urine either as conjugated or unconjugated forms. The oncology patient’s urine enters sewage system, reaching wastewater treatment plants (WWTP) that are unable to remove cytostatics, which will inevitably end up in the aquatic environment. In order to minimize this serious environmental and health concern, several technologies to remove these drugs from WWTP effluent are being developed and/or implemented, including nanofiltration, photoassisted oxidation processes, and ozonation. This chapter will review the environmental levels of the most prevalent cytostatic drugs and the challenges associated with the removal of these emerging contaminants from WWTP effluent.
Type: bookPart
Appears in Collections:BIO - Publicações - Capítulos de Livros
CHRC - Publicações - Capítulos de Livros

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