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Title: Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
Authors: Oliveira, Teresa
Lopes de Castro, José
Fragoso, João
Pereira, Alfredo
Manca, Antonio
Vitale-Broverone, Chiara
Queiroga, Cristina
Reis, Joana
Editors: Simões, José António
Marinho, Daniel
Completo, António
Ramos, António
Keywords: resorbable cement
percutaneous vertebroplasty
in vivo
Issue Date: Feb-2019
Publisher: UA Editora - Universidade de Aveiro
Abstract: Polymethylmethacrylate (PMMA) based cements are widely used for vertebroplasty. However, PMMA has disadvantages. The purpose of the present work was to test in vivo a new resorbable injectable composite cement – Spine-Ghost. The paste was percutaneously injected in bone defects manually drilled in L4 vertebral bodies of eight mature Merino sheep (Group B). A control group of eight sheep was injected with a known commercial calcium sulphate-based biphasic cement (Group A). After the 6-month implantation period the samples were assessed by micro-CT and histological studies. All sheep completed the 6-month implantation period. Cement resorption and new bone formation were observed in all samples with no signs of infection or inflammation.
Type: article
Appears in Collections:MVT - Artigos em Livros de Actas/Proceedings

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