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Title: Antioxidant activity and cholinesterase inhibition studies of four flavouring herbs from Alentejo
Authors: Arantes, Sílvia
Piçarra, Andreia
Candeias, M. Fátima
Caldeira, A. Teresa
Martins, M. Rosário
Editors: Salgueiro, Ligia
Cavaleiro, Carlos
Cabral, Celia
Keywords: aromatic plants
antioxidant activity
cholinesterase inhibition
Issue Date: 2016
Publisher: Universidade de Coimbra, Faculdade de Farmácia
Citation: Sílvia Arantes, Andreia Piçarra, M. Fátima Candeias, A. Teresa Caldeira, M. Rosário Martins (2016). Antioxidant activity and cholinesterase inhibition studies if four flavoring herb from Alentejo. Proceedings of 6th International Congress of Aromatic and Medicinal Plants (Eds Lígia Salgueiro, Carlos Cavaleiro, Célia Cabral), University of Coimbra. ISBN: 978-989-95050-1-8.
Abstract: In Alzheimer’s disease, the most common form of dementia, the loss of cholinergic neurons leads to the progressive reduction of acetylcholine in the brain, resulting cognitive impairment. Inhibition of the hydrolysis of acetylcholine by blocking acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) has been considered as a potential target in the treatment of Alzheimer’s disease. Essential oils and extracts of aromatic plants may have an important role in the oxidative stress protection. Traditionally, in Alentejo (Portugal), aromatic herbs Calamintha nepeta, Foeniculum vulgare, Mentha spicata and Thymus mastichina are often used by local population as condiments in food preparations. In this study, essential oils (EOs) and aqueous extracts (decoction waters) of these flavouring herbs were selected in order to evaluate its antioxidant potential and ability to inhibit AChE and BChE activities. Results suggest the potential use of EOs and extracts as nutraceutical or pharmaceutical preparations in the prevention of the oxidative stress and degenerative diseases.
ISBN: 978-989-95050-1-8
Type: article
Appears in Collections:MED - Artigos em Livros de Actas/Proceedings
QUI - Artigos em Livros de Actas/Proceedings
HERCULES - Artigos em Livros de Actas/Proceedings

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