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|Title: ||Palladium catalysed sequential imine arylation/Suzuki–Miyaura coupling: synthesis of a-(biarylyl)benzylamines|
|Authors: ||Marques, Carolina S.|
Prates Ramalho, J.P.
Burke, Anthony J.
|Issue Date: ||2015|
|Citation: ||Marques, Carolina S.; Locati, Abel; Prates Ramalho, J.P.; Burke, Anthony J.Palladium catalysed sequential imine arylation/Suzuki–Miyaura coupling: synthesis of a-(biarylyl)benzylamines, Tetrahedron, 71, 21, 3314-3324, 2015.|
|Abstract: ||report an innovative, high yielding one-pot sequential catalytic imine arylation/SuzukieMiyaura
cross-coupling reaction, which converts suitably activated imine substrates to various biarylarylmethyl
amine products using several commercial Pd catalysts. Many biarylarylmethyl amine molecules are biologically
active. Insightful computational studies detail the mechanism of the imine arylation process.
The sequence of reactions is likely to be dependent on the reaction conditions.|
|Other Identifiers: ||00404020|
|Appears in Collections:||CQE - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica|
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