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Title: Spine-Ghost: A New Bioactive Cement for Vertebroplasty
Authors: Vitale-Brovarone, Chiara
Pontirolli, Lucia
Novajra, Giorgia
Tcacencu, Ion
Reis, Joana
Manca, Antonio
Editors: Ginebra, Maria-Pau Edgar B. Montufar and Roman A. Perez
Canal, Cristina
Espanhol, Montserrat
Montufar, Edgar
Perez, Roman
Keywords: vertebroplasty
resorbable cement
mesoporous bioactive glass
Issue Date: 2015
Publisher: Key Engineering Materials
Citation: Vitale-Brovarone, C, Pontirolli L, Novajra, G, Tcacencu, I, Reis, J & Manca, A (2015): Spine-Ghost: a new bioactive Cement for Vertebroplasty. Key Engineering Materials 631 (26): 43-47.
Abstract: An innovative, resorbable and injectable composite cement (Spine-Ghost) to be used for augmentation and restoration of fractured vertebrae was developed. Type III α-calcium sulfate hemihydrate (CSH) was selected as the bioresorbable matrix, while spray-dried mesoporous bioactive particles (SD-MBP, composition 80/20% mol SiO2/CaO), were added to impart high bioactive properties to the cement; a glass-ceramic containing zirconia was chosen as a second dispersed phase, in order to increase the radiopacity of the material. After mixing with water, an injectable paste was obtained. The developed cement proved to be mechanically compatible with healthy cancellous bone, resorbable and bioactive by soaking in simulated body fluid (SBF), cytocompatible through in-vitro cell cultures and it could be injected in ex-vivo sheep vertebra. Comparisons with a commercial control were carried out.
Type: article
Appears in Collections:MVT - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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