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http://hdl.handle.net/10174/8856
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| Title: | BorArAm - Catalytic Asymmetric Arylating Cyclizations: A New Route to Chiral Bicyclic Amines |
| Authors: | Mendes, Paulo J.
Viana, H.
Marques, C. S.
Burke, Anthony J. |
| Keywords: | Asymmetric Catalysis
Bicyclic Amines |
| Issue Date: | 2013 |
| Publisher: | Sociedade Portuguesa de Química |
| Citation: | H. Viana, C. S. Marques, Paulo J. Mendes, Anthony J. Burke, “BorArAm - Catalytic Asymmetric Arylating Cyclizations: A New Route to Chiral Bicyclic Amines”, 10º Encontro Nacional de Química Orgânica, 1º Simpósio Luso-Brasileiro de Química Orgânica, September 4-6, 2013, Lisbon, Portugal, Book of Abstracts PC103 |
| Abstract: | Nowadays neurodegenerative diseases such as Alzheimer’s disease and Parkinson disease represent a worldwide health threat. Rasagiline is one well-known medication for the treatment of Parkinson's disease, but more and cheaper alternatives are required.1 For this reason, our group is currently investigating a new catalytic asymmetric arylating2 cyclization route - borylation-arylation-amination (BorArAm) (Scheme 1) giving useful potential lead compounds based on the rasagiline core structure for treating these diseases.
Our results will be discussed in this communication. |
| URI: | http://10enqo.eventos.chemistry.pt/?ver=sprogram
http://hdl.handle.net/10174/8856 |
| Type: | lecture |
| Appears in Collections: | QUI - Comunicações - Em Congressos Científicos Internacionais
CQE - Comunicações - Em Congressos Científicos Internacionais
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CQE - Comunicações - Em Congressos Científicos Internacionais /
