Please use this identifier to cite or link to this item: http://hdl.handle.net/10174/6492

Title: Evidence of a bimodal effect on Saccharomyces cerevisiae UE-ME3 by vanadium (V) stress - a dual response to different V2O5 medium concentration detected in the rate growth, GSH/GSSG, G6PD, CAT T and GR enzymatic activities
Authors: Alves-Pereira, I
Rosado, T
Ferreira, R
Editors: Mendez-Vilas, A
Keywords: S. cerevisiae
oxidative stress
vanadium
Issue Date: 2009
Publisher: World scientific publishing Co
Citation: Alves-Pereira I, Rosado T, Ferreira R (2009) – Evidence of a bimodal effect on Saccharomyces cerevisiae UE-ME3 by vanadium (V) stress - a dual response to different V2O5 medium concentration detected in the rate growth, GSH/GSSG, G6PD, CAT T and GR enzymatic activities, In: Current research topics in applied microbiology and microbial biotechnology (Mendez-Vilas ed.), pp 245-249, World scientific publishing Co, Singapore. (ISBN: 978-981-283-754-7).
Abstract: The aim of this work was to evaluate the effects of five V2O5 medium concentrations ranging from 0.5 to 2.0 mM on cell viability, redox status and antioxidants enzymes of wine yeast S. cerevisiae UE-ME3. A slightly decrease of yeast cells growth rate for 0.5 and 1.0 mM, and a significantly decrease for 1.5 and 2.0 mM were observed. Conversely, a significantly increase of G6PD activity and GSH/GSSG ratio for 0.5 mM V2O5, and a significantly decrease of GR and CAT T activities for 0.5 and 1.0 mM also occurs. Furthermore, for V2O5, ranging between 1.0 and 2.0 mM, we observed a significantly decrease of G6PD and GSH/GSSG ratio, occurring, at the same conditions a reverse effect on GR and CAT T activities, with a significant increase of GR for 1.5 and 2.0 mM. We suppose that bimodal response of S. cerevisiae to vanadium pentoxide, eventually mediated by NADPH and GSH level, rule cell death.
URI: http://hdl.handle.net/10174/6492
ISBN: 978-981-283-754-7
Type: bookPart
Appears in Collections:ICAAM - Publicações - Capítulos de Livros
QUI - Publicações - Capítulos de Livros

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