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Title: Voltammetric Study of the Antihistamine Drug Bilastine: Anodic Characterization and Quantification Using a Reusable MWCNTs Modified Screen Printed Carbon Electrode
Authors: Ginja Teixeira, Jorge
Oliveira, João
Editors: Campuzano Ruiz, Susana
Keywords: Antihistamine
Multi-walled carbon nanotubes (MWCNTs)
Screen printed carbon electrode (SPCE)
Voltammetric determination
Issue Date: 8-Nov-2020
Publisher: Wiley
Citation: Jorge Ginja Teixeira, João Oliveira, Electroanalysis, 08 November 2020 (10 pages)
Abstract: The anodic behaviour and the electroanalytical quantification of the second‐generation antihistamine bilastine (BIL) were investigated for the first time. A multi‐walled carbon nanotubes (MWCNTs) film‐coated screen printed carbon electrode (SPCE), as well as cyclic (CV) and linear sweep (LSV) voltammetry, were used for that purpose. The results showed that BIL undergoes an irreversible two‐electron oxidation process at the MWCNTs‐SPCE sensor. It was also found that the sensor can be reused after a simple and rapid reconditioning procedure. The proposed method was applied to the quantification of BIL in pharmaceutical formulations and spiked urine samples, and good recoveries were obtained.
ISSN: 1521-4109
Type: article
Appears in Collections:HERCULES - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica
QUI - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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