Please use this identifier to cite or link to this item:
http://hdl.handle.net/10174/17022
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Title: | Production of Green biocides for cultural heritage- novel biotechnological solutions |
Authors: | Silva, M Rosado, T Teixeira, D Candeias, AJ Caldeira, A T |
Keywords: | Cultural Heritage Bioactive compounds Lipopeptides |
Issue Date: | 2015 |
Citation: | Mara Silva, Tânia Rosado, Dora Teixeira, António Candeias, Ana Teresa Caldeira (2015).Production of Green biocides for cultural heritage- novel biotechnological solutions. International Journal of Conservation Science. Volume 6: 519-530 |
Abstract: | The growth control of microflora in cultural and built heritage is usually performed by
treatments using chemicals that have high toxicity. Thus it is crucial to develop strategies to
discover new bioactive molecules and establish effective approaches against the effectively
biodeteriogenic agents, which are responsible for degradation of cultural and built heritage,
without detriment to the environment. Bacillus sp. produce a high number of secondary
metabolites, some with antibiotic properties which can be used against biodeteriogenic
filamentous fungi, source of serious damage in historic materials. These antagonistic
proprieties are due to the production of bioactive lipopeptides which exhibit antifungal activity
in the stationary phase of bacteria growth, being associated to secondary metabolism. A
combined methodology using antifungal tests, chromatographic techniques, FTIR-ATR,
microscopic approaches and simulations assays allowed the detection of antifungal potential
and a rapid identification of these ground-breaking bioactive compounds without the need of
previous total isolation. This novel green biocides show a great potential for future application
in cultural and built heritage rehabilitation being an effective alternative to the chemical
compounds usually applied. |
URI: | http://hdl.handle.net/10174/17022 |
Type: | article |
Appears in Collections: | QUI - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica HERCULES - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica
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